Pappataci fever - an acute natural focal infection caused by a filterable arbovirus and flowing with short febrile syndrome. Pappataci fever accompanied by febrile fever, headache and muscle pain, eye reactions (symptoms of Pick and Taussig), flushing of the face and neck hemorrhages, meningeal phenomena, long asthenic syndrome alternative buy cipro online. Recognition pappatachi fever is carried out on the basis of epidemiological history, clinical, serological and virological studies. Treatment of symptomatic fever pappatachi; It includes detoxication therapy, taking antipyretic, cardiovascular agents, vitamins.
Pappataci fever (a mosquito, a three-day, dog disease) - transmissible viral disease with a typical short-term fever, severe myalgia, pathognomonic reactions on the part of the eye, neurological symptoms. The territory spread pappataci fever coincides with the habitat of mosquitoes, carriers and covers the tropical and subtropical regions (the Mediterranean, the Balkans, the Middle East, East and West Africa, South and Southeast Asia, the North Caucasus and Transcaucasia, Central Asia). Incidence pappataci fever is characterized by a strong spring-summer season with two peaks (May-June, July-August), caused by mosquitoes breeding. Pappataci fever usually occurs in non-immune persons coming for the first time in endemic areas; the indigenous population has immunity due to disease, suffering in early childhood.
Pappataci fever causing serotypes 5 filterable virus genomic RNA of the family bunyanovirusov. Viral particles are heat-sensitive, disinfectants, however, resistant to low temperatures; stored in the dried state to 3-7 months. There are natural foci and anthropurgic pappatachi fever.
The source of the virus are infected with wild and synanthropic rodents or sick person in a stage of viremia. Specific carriers of the virus are the pappataci fever flying blood-sucking insects - mosquitoes female Phlebotomus papatasii. When feeding the blood of infected animals and humans, is in the initial stage of the disease, pappatachi fever virus enters the body of mosquito, breeds and remains there for life, handed down to future generations transovarially. Man pappataci fever is transmitted most often transmissible through bites of infected mosquitoes; It does not exclude the possibility of infection through parenteral insufficiently treated medical instruments.
Mosquito bites are accompanied by reddening of the skin, swelling, itching nodule formation, scratching. In humans pappatachi fever virus infects cells of the monocyte-macrophage system, which quickly reproduced during the incubation period and in the first 2-3 days of the disease enters the blood stream to the development of a generalized viremia. Because certain neurotropic, pappatachi fever virus settles into the cells of the central nervous system, causing a violation of its functions, leading to cerebral hypertension. The changes also affect the small blood vessels and muscles.
The incubation period pappataci fever is 3 to 9 days. The disease has an acute, sudden onset of fever with severe and sudden temperature jump to 38-41˚C. Pappataci fever accompanied by severe headache in the temporal and frontal areas; myalgia sharply, especially in the calf muscles, back and waist; pain along the nerve trunks. There have pathognomonic ocular reactions: a limited injection of the sclera at the outer corners of the eyes in the form of a triangle with the apex pointing to the cornea (the Peak symptom), severe pain when moving the eyes, pressure on the eyeball, and you try to pick up with your fingers the upper eyelid (Taussig symptom), photophobia, conjunctivitis .
Noticeable puffiness of the face and neck, redness of the mucous membrane pharynx with point hemorrhages, swelling of the tongue and palatine arches. On the lips may cause herpetic lesions on the skin - makuleznoy or urticaria and punctate hemorrhages. There may be nasal and gastrointestinal bleeding. In severe forms pappataci fever appear neurological symptoms: dizziness, hypersensitivity, meningeal phenomena, anxiety, agitation, delirium, loss of consciousness. Often there is bloating, nausea, vomiting, rapid up to 5-6 times a day loose stools with mucus.
The duration of febrile period determined by the severity of the clinical course pappataci fever: in mild fever phase lasts 1-2 days, while moderate - 3-4 days in severe - up to 8 days. The temperature is reduced to normal or critical subfebrile indicators, which is accompanied by severe weakness and drenching sweat, bradycardia. convalescence period long; lasts for several weeks or occurs with severe asthenia, neuralgia, depression, and decreased performance. Sometimes, there are trophic disorders manifested hair loss, brittle nails. Complications pappataci fever are rare in the form of pneumonia, infectious psychosis.
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